Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | PDE1B | Q01064 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5451833 | 0.88 | PDE10A (0.61) | ALDH1A1LMNASMN1; SMN2PDE10APDE1B | |
| SCHEMBL17283025 | 0.87 | ALDH1A1 (0.49) | ALDH1A1LMNASMN1; SMN2PDE10APDE1B | |
| SCHEMBL5452368 | 0.87 | ADORA2A (0.51) | ALDH1A1LMNASMN1; SMN2PDE10APDE1B | |
| SCHEMBL6078154 | 0.86 | ALDH1A1 (0.48) | ALDH1A1LMNASMN1; SMN2PDE10APDE1B | |
| SCHEMBL21174200 | 0.81 | TLR7 (0.57) | ALDH1A1LMNASMN1; SMN2PDE10APDE1B | |
| SCHEMBL5467849 | 0.80 | PDE10A (0.44) | ALDH1A1LMNASMN1; SMN2PDE10APDE1B | |
| SCHEMBL5466010 | 0.79 | ADORA2A (0.53) | ALDH1A1PDE10APDE1BMAPTKDM4E | |
| SCHEMBL5465357 | 0.77 | HPGD (0.64) | ALDH1A1LMNASMN1; SMN2KMT2AHPGD | |
| SCHEMBL4928309 | 0.76 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL15720273 | 0.75 | ADORA2A (0.46) | KMT2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070203159-A1 | Purine compounds | UNIVERSITETET I OLSO (NO) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203159-A1 | Purine compounds | PNP, UMPS, TYMP | ALDH1A1 2044/4885LMNA 2001/4885SMN1; SMN2 3727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.