Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | QPCT | Q16769 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11488553 | 0.91 | ALDH1A1 (0.71) | SMN1; SMN2HTTALDH1A1ALOX12KDM4E | |
| SCHEMBL4402140 | 0.84 | ALDH1A1 (0.63) | SMN1; SMN2HTTALDH1A1ALOX12KDM4E | |
| SCHEMBL14093828 | 0.84 | ALDH1A1 (0.66) | SMN1; SMN2HTTALDH1A1ALOX12KDM4E | |
| SCHEMBL31349696 | 0.84 | ALDH1A1 (0.66) | SMN1; SMN2HTTALDH1A1ALOX12KDM4E | |
| SCHEMBL31349697 | 0.84 | ALDH1A1 (0.66) | SMN1; SMN2HTTALDH1A1ALOX12KDM4E | |
| SCHEMBL19822471 | 0.83 | POLB (0.69) | SMN1; SMN2HTTALDH1A1ALOX12KDM4E | |
| SCHEMBL11839412 | 0.83 | ALDH1A1 (0.70) | SMN1; SMN2ALDH1A1ALOX12KDM4EPOLB | |
| SCHEMBL5739547 | 0.82 | ALDH1A1 (0.66) | SMN1; SMN2HTTALDH1A1ALOX12KDM4E | |
| Hydrochloric Acid SCHEMBL11837771 | 0.81 | ALDH1A1 (0.68) | SMN1; SMN2ALDH1A1ALOX12KDM4EPOLB | |
| SCHEMBL6957793 | 0.80 | ALDH1A1 (0.76) | SMN1; SMN2HTTALDH1A1ALOX12KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |