Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | NPC1 | O15118 | 6/20 | 0.67 |
| ▸ | RAB9A | P51151 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14096454 | 0.84 | MAPT (0.76) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL14096362 | 0.82 | KMT2A (0.71) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL14096341 | 0.81 | RAB9A (1.00) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL14096451 | 0.80 | KMT2A (0.82) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL15702660 | 0.80 | ALDH1A1 (0.75) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5448328 | 0.79 | RAB9A (0.73) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5446600 | 0.79 | ALDH1A1 (0.78) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL31504713 | 0.79 | MAPT (0.56) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL31504716 | 0.78 | MAPT (0.61) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL31504718 | 0.78 | RAB9A (0.58) | MAPTNPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |