Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449848 | 1.00 | ZDHHC7 (0.38) | ZDHHC7LMNADNM1PLA2G1BPLA2G2A | |
| SCHEMBL5433349 | 1.00 | ZDHHC7 (0.38) | ZDHHC7LMNADNM1PLA2G1BPLA2G2A | |
| SCHEMBL5442898 | 1.00 | ZDHHC7 (0.38) | ZDHHC7LMNADNM1PLA2G1BPLA2G2A | |
| SCHEMBL11646858 | 1.00 | ZDHHC7 (0.38) | ZDHHC7LMNADNM1PLA2G1BPLA2G2A | |
| SCHEMBL5444537 | 0.98 | OPRM1 (0.37) | ZDHHC7LMNADNM1PLA2G1BPLA2G2A | |
| SCHEMBL4543524 | 0.91 | DNM1 (0.35) | DNM1TSHR | |
| SCHEMBL29065834 | 0.81 | OPRM1 (0.39) | LMNADNM1PLA2G1BPLA2G2ATSHR | |
| SCHEMBL5432519 | 0.80 | OPRM1 (0.39) | LMNADNM1PLA2G1BPLA2G2ATSHR | |
| SCHEMBL5436774 | 0.80 | OPRM1 (0.39) | LMNADNM1PLA2G1BPLA2G2ATSHR | |
| SCHEMBL5442791 | 0.80 | OPRM1 (0.39) | LMNADNM1PLA2G1BPLA2G2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2500368-A2 | Catalyst and process for producing a rigid polyurethane foam | Tosoh Corporation (JP) | 2012-09-19 | — | — | EP | disclosed |
| US-20070043132-A1 | Catalyst and process for producing a rigid polyurethane foam | TOSOH CORPORATION (JP) | 2007-02-22 | — | — | US | disclosed |
| US-20040082465-A1 | Catalyst and process for producing a rigid polyurethane foam | TOSOH CORPORATION (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1382624-A1 | Catalyst and process for producing a rigid polyurethane foam | Tosoh Corporation (JP) | 2004-01-21 | — | — | EP | disclosed |