Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PANK3 | Q9H999 | 4/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459054 | 0.89 | MEN1 (0.48) | KMT2AMEN1PANK3P2RY1CA12 | |
| SCHEMBL5465480 | 0.88 | KMT2A (0.63) | KMT2AMEN1PANK3P2RY1CA12 | |
| SCHEMBL5451017 | 0.88 | GFER (0.50) | KMT2AP2RY1MAPTNPC1RAB9A | |
| SCHEMBL5466982 | 0.84 | MAPT (0.47) | KMT2AMEN1PANK3P2RY1CA12 | |
| SCHEMBL5467032 | 0.82 | PANK3 (0.46) | KMT2AMEN1PANK3P2RY1CA12 | |
| SCHEMBL5460053 | 0.81 | GLA (0.48) | KMT2APANK3P2RY1CA12CA1 | |
| SCHEMBL5454308 | 0.81 | NAMPT (0.50) | KMT2AMEN1PANK3CA12CA1 | |
| SCHEMBL5459962 | 0.81 | PANK3 (0.47) | KMT2AMEN1PANK3P2RY1CA12 | |
| SCHEMBL5458442 | 0.80 | MAPT (0.47) | KMT2AMEN1PANK3CA12CA1 | |
| SCHEMBL5469441 | 0.79 | PANK3 (0.45) | KMT2AMEN1PANK3P2RY1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | KMT2A 1350/4885MEN1 1828/4885PANK3 3325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.