Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.55 |
| ▸ | MAPT | P10636 | 14/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.55 |
| ▸ | HPGD | P15428 | 9/20 | 0.55 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31379816 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL5457757 | 0.77 | PTPN1 (0.54) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL5447655 | 0.76 | FLT3 (0.65) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL17018764 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL31147391 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL2688221 | 0.72 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL3397070 | 0.72 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL31147499 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL17797450 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL21261114 | 0.71 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
| EP-1670804-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC Biotech AG (DE) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005023818-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC BIOTECH AG (DE) | 2005-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | TBCA, PARK7, NFATC1 | ALDH1A1 1153/4885MAPT 21/4885KDM4E 3417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.