Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.61 |
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5448299 | 0.87 | NPC1 (0.66) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL14096526 | 0.76 | KMT2A (1.00) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL14096559 | 0.75 | NPC1 (1.00) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL14096417 | 0.74 | ALDH1A1 (0.71) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL28600551 | 0.71 | MAPT (0.80) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL6848441 | 0.71 | NPC1 (0.76) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL23011772 | 0.70 | KCNK3 (0.82) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL31504702 | 0.69 | ALDH1A1 (0.55) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL31504705 | 0.69 | ALDH1A1 (0.59) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL8291149 | 0.69 | NPC1 (0.67) | NPC1RAB9AALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |