Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 4/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20654098 | 0.88 | CA1 (0.34) | BRD4CREBBPDPP4DPP8DPP7 | |
| SCHEMBL1937119 | 0.80 | — | — | |
| SCHEMBL24535856 | 0.80 | — | — | |
| SCHEMBL14140112 | 0.77 | BRD4 (0.33) | BRD4CREBBPDPP4DPP8DPP7 | |
| SCHEMBL21698444 | 0.77 | BRD4 (0.33) | BRD4CREBBPDPP4DPP8DPP7 | |
| SCHEMBL2080419 | 0.77 | BRD4 (0.33) | BRD4CREBBPALOX5 | |
| SCHEMBL5188434 | 0.72 | ALDH1A1 (0.32) | BRD4CREBBP | |
| SCHEMBL1717097 | 0.72 | ITGB1 (0.37) | BRD4CREBBPDPP4DPP8DPP7 | |
| SCHEMBL8963078 | 0.72 | — | — | |
| SCHEMBL30913158 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007095586-A2 | NEURONAL PAIN PATHWAY MODULATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-08-23 | — | — | WO | disclosed |
| US-20070129578-A1 | Method for the production of 2,2'-dihydroxybiphenyls | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-07 | — | — | US | disclosed |
| EP-1682473-A1 | METHOD FOR THE PRODUCTION OF 2,2'-DIHYDROXYBIPHENYLS | BASF Aktiengesellschaft (DE) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005042454-A1 | METHOD FOR THE PRODUCTION OF 2,2'-DIHYDROXYBIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-12 | — | — | WO | disclosed |
| US-4058462-A | System for sustained release of phenolic material from porous granules of insoluble polymeric phenolic complexes | GAF CORPORATION (US) | 1977-11-15 | — | — | US | disclosed |
| US-3985540-A | Metal complexes of hydroxyquinoline and polymeric porous granules | GAF CORPORATION (US) | 1976-10-12 | — | — | US | disclosed |
| US-3970606-A | N-vinyl lactam interpolymers useful as thickening agents | GAF CORPORATION (US) | 1976-07-20 | — | — | US | disclosed |
| US-3954682-A | GRANULES OR BEADS | GAF CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129578-A1 | Method for the production of 2,2'-dihydroxybiphenyls | HAO2, DAO, DDO | BRD4 1465/4885CREBBP 4450/4885DPP4 2181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.