SCHEMBL5453541

SCHEMBL5453541

NS(=O)(=O)c1ccc(NC(=S)Nc2ccc(Cl)c(Cl)c2)cc1

nearest known ligand 0.79

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.79
MAPT P10636 4/20 0.79
MEN1 O00255 3/20 0.79
KMT2A Q03164 3/20 0.79
HTT P42858 1/20 0.74
PTPN7 P35236 2/20 0.65
CA2 P00918 9/20 0.63
CA1 P00915 7/20 0.63
CA9 Q16790 4/20 0.63
CA4 P22748 1/20 0.63
CA12 O43570 1/20 0.62
IDO1 P14902 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6692412 0.86 CA2 (0.76) MAPTMEN1KMT2AHTTCA2
SCHEMBL31310428 0.84 CA1 (0.74) ALDH1A1MAPTMEN1KMT2APTPN7
SCHEMBL5452737 0.83 CA1 (0.75) ALDH1A1MEN1KMT2ACA2CA1
SCHEMBL4555003 0.82 IDO1 (0.78) ALDH1A1MAPTMEN1KMT2AHTT
SCHEMBL6817994 0.80 ALDH1A1 (0.55) ALDH1A1MAPTMEN1KMT2AHTT
SCHEMBL15840806 0.79 ALDH1A1 (0.67) ALDH1A1MAPTMEN1KMT2A
SCHEMBL15840508 0.79 ALDH1A1 (0.57) ALDH1A1MAPTMEN1KMT2AHTT
SCHEMBL3404661 0.79 PTPN7 (0.75) ALDH1A1MAPTMEN1KMT2APTPN7
SCHEMBL7615242 0.79 PTPN7 (1.00) ALDH1A1MEN1KMT2APTPN7CA2
SCHEMBL6815897 0.79 IDO1 (0.69) ALDH1A1MAPTMEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101129295-B There is the binary initiator system of good storage stability and especially suitable for acidic system HERAEUS KULZER GMBH (DE) 2016-02-10 CN disclosed
CN-101129295-A 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems HERAEUS KULZER GMBH (DE) 2008-02-27 CN disclosed
US-20070040151-A1 Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems HERAEUS KULZER GMBH (DE) 2007-02-22 US disclosed