Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5453554 | 1.00 | KCNH2 (0.61) | KCNH2ATMKMT2AMEN1KDM4E | |
| SCHEMBL18902248 | 0.89 | KCNH2 (0.76) | KCNH2ATMKMT2AMEN1KDM4E | |
| SCHEMBL5459048 | 0.80 | KMT2A (0.59) | ATMKMT2AMEN1KDM4ENPC1 | |
| SCHEMBL5459039 | 0.80 | KMT2A (0.59) | ATMKMT2AMEN1KDM4ENPC1 | |
| SCHEMBL17022020 | 0.77 | KCNH2 (0.79) | KCNH2ATMKMT2AMEN1KDM4E | |
| Hydrochloric Acid SCHEMBL17006318 | 0.76 | KCNH2 (0.79) | KCNH2ATMKMT2AMEN1KDM4E | |
| SCHEMBL5453655 | 0.76 | KMT2A (0.66) | KCNH2ATMKMT2AMEN1ALDH1A1 | |
| SCHEMBL17022007 | 0.76 | KCNH2 (0.66) | KCNH2ATMKMT2AMEN1KDM4E | |
| SCHEMBL2682306 | 0.76 | KCNH2 (1.00) | KCNH2ATMKMT2AMEN1KDM4E | |
| SCHEMBL17021989 | 0.76 | KCNH2 (0.72) | KCNH2ATMKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | claimed |
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | TBCA, PARK7, NFATC1 | KCNH2 3409/4885ATM 2057/4885KMT2A 4785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.