Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5457244 | 0.90 | PTPN1 (0.53) | PPARGPPARA | |
| SCHEMBL5444129 | 0.87 | PPARG (0.63) | PPARGPPARA | |
| SCHEMBL5447528 | 0.87 | PPARG (0.63) | PPARGPPARA | |
| SCHEMBL5448677 | 0.80 | PPARG (0.61) | PPARGPPARA | |
| SCHEMBL3046273 | 0.79 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL5444126 | 0.79 | PTPN1 (0.51) | PPARGPPARA | |
| SCHEMBL5451083 | 0.79 | PTPN1 (0.51) | PPARGPPARA | |
| SCHEMBL5445393 | 0.79 | PPARG (0.67) | PPARGPPARA | |
| SCHEMBL20553481 | 0.78 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL20553479 | 0.78 | PPARG (1.00) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123495-A1 | PYRROLO-NAPHTHYL ACIDS AND METHODS FOR USING THEM | WYETH (US) | 2007-05-31 | — | — | US | claimed |
| EP-1781641-A1 | PYRROLO-NAPHTHYL ACIDS AS PAI-1 INHIBITORS | Wyeth (US) | 2007-05-09 | — | — | EP | claimed |
| US-7186749-B2 | Pyrrolo-naphthyl acids and methods for using them | WYETH (US) | 2007-03-06 | — | — | US | claimed |
| US-20060052349-A1 | Pyrrolo-naphthyl acids and methods for using them | WYETH (US) | 2006-03-09 | — | — | US | claimed |
| WO-2006023864-A1 | PYRROLO-NAPHTHYL ACIDS AS PAI-1 INHIBITORS | WYETH (US) | 2006-03-02 | — | — | WO | claimed |
| US-20070123495-A1 | PYRROLO-NAPHTHYL ACIDS AND METHODS FOR USING THEM | WYETH (US) | 2007-05-31 | — | — | US | disclosed |
| EP-1781641-A1 | PYRROLO-NAPHTHYL ACIDS AS PAI-1 INHIBITORS | Wyeth (US) | 2007-05-09 | — | — | EP | disclosed |
| US-7186749-B2 | Pyrrolo-naphthyl acids and methods for using them | WYETH (US) | 2007-03-06 | — | — | US | disclosed |
| US-20060052349-A1 | Pyrrolo-naphthyl acids and methods for using them | WYETH (US) | 2006-03-09 | — | — | US | disclosed |
| WO-2006023864-A1 | PYRROLO-NAPHTHYL ACIDS AS PAI-1 INHIBITORS | WYETH (US) | 2006-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123495-A1 | PYRROLO-NAPHTHYL ACIDS AND METHODS FOR USING THEM | SERPINE1, SERPINC1, SERPINB1 | PPARG 266/4885PPARA 228/4885 |
| US-20060052349-A1 | Pyrrolo-naphthyl acids and methods for using them | SERPINE1, SERPINC1, SERPINB1 | PPARG 266/4885PPARA 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.