Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 4/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.54 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5453595 | 1.00 | NQO2 (0.69) | NQO2PTGS1PTGS2TUBB1ALDH1A1 | |
| SCHEMBL5453588 | 1.00 | NQO2 (0.69) | NQO2PTGS1PTGS2TUBB1ALDH1A1 | |
| SCHEMBL20457122 | 0.90 | NQO2 (0.76) | NQO2PTGS1PTGS2TUBB1ALDH1A1 | |
| SCHEMBL22383911 | 0.90 | NQO2 (0.76) | NQO2PTGS1PTGS2TUBB1ALDH1A1 | |
| SCHEMBL31474400 | 0.90 | NQO2 (0.76) | NQO2PTGS1PTGS2TUBB1ALDH1A1 | |
| SCHEMBL7803180 | 0.86 | ESR1 (0.64) | NQO2PTGS1PTGS2ALDH1A1MAPT | |
| SCHEMBL9465277 | 0.84 | PTGS1 (0.75) | NQO2PTGS1PTGS2TUBB1ALDH1A1 | |
| SCHEMBL9465510 | 0.84 | PTGS1 (0.75) | NQO2PTGS1PTGS2TUBB1ALDH1A1 | |
| SCHEMBL9465505 | 0.84 | PTGS1 (0.75) | NQO2PTGS1PTGS2TUBB1ALDH1A1 | |
| SCHEMBL9465281 | 0.84 | PTGS1 (0.75) | NQO2PTGS1PTGS2TUBB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066825-A1 | Chiral ligands and their transition metal complexes | LANXESS DEUTSCHLAND GMBH (DE) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066825-A1 | Chiral ligands and their transition metal complexes | PICALM, CACYBP, SLC39A14 | NQO2 4095/4885PTGS1 4145/4885PTGS2 3916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.