Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5448276 | 0.76 | HDAC1 (0.55) | KMT2ARAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4485571 | 0.76 | KMT2A (0.68) | KMT2APOLBL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL5448334 | 0.76 | KDM4E (0.58) | KMT2APOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4276208 | 0.75 | KMT2A (0.63) | KMT2APOLBSMN1; SMN2L3MBTL1NPSR1 | |
| SCHEMBL5446773 | 0.75 | KDM4E (0.48) | SMN1; SMN2NPSR1LMNAALDH1A1HDAC6 | |
| SCHEMBL5446738 | 0.74 | ALDH1A1 (0.51) | POLBRAB9ANPC1SMN1; SMN2NPSR1 | |
| SCHEMBL5453726 | 0.73 | DPP7 (0.50) | KMT2ARAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL17850457 | 0.73 | KMT2A (0.71) | KMT2ARAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10288644 | 0.73 | KMT2A (0.71) | KMT2ARAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3196036 | 0.73 | KMT2A (0.71) | KMT2APOLBSMN1; SMN2L3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167499-A1 | Biaryl linked hydroxamates: preparation and pharmaceutical applications | A*BIO PTE LTD. (SG) | 2007-07-19 | — | — | US | disclosed |
| US-20070167499-A1 | Biaryl linked hydroxamates: preparation and pharmaceutical applications | A*BIO PTE LTD. (SG) | 2007-07-19 | — | — | US | disclosed |
| US-20070167499-A1 | Biaryl linked hydroxamates: preparation and pharmaceutical applications | A*BIO PTE LTD. (SG) | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167499-A1 | Biaryl linked hydroxamates: preparation and pharmaceutical applications | HDAC1, HDAC11, HDAC2 | KMT2A 80/4885POLB 525/4885RAB9A 4613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.