SCHEMBL5453987

SCHEMBL5453987

Cc1ccc(NC(N)=S)c(C)c1

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.57
KMT2A Q03164 4/20 0.57
ALDH1A1 P00352 4/20 0.57
SMN1; SMN2 Q16637 4/20 0.57
GAA P10253 2/20 0.57
RAB9A P51151 2/20 0.54
NPC1 O15118 1/20 0.54
HTT P42858 2/20 0.53
KDM4E B2RXH2 1/20 0.53
RAPGEF4 Q8WZA2 1/20 0.52
CYP1A2 P05177 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30817854 1.00 MEN1 (0.57) MEN1KMT2AALDH1A1SMN1; SMN2GAA
SCHEMBL32670809 0.84 ALDH1A1 (0.68) MEN1KMT2AALDH1A1SMN1; SMN2GAA
SCHEMBL5528760 0.84 ALDH1A1 (0.68) MEN1KMT2AALDH1A1SMN1; SMN2GAA
SCHEMBL31388347 0.83 KMT2A (0.71) MEN1KMT2AALDH1A1SMN1; SMN2GAA
SCHEMBL11143189 0.83 RAB9A (0.57) MEN1KMT2AALDH1A1SMN1; SMN2GAA
SCHEMBL10670396 0.82 GAA (0.51) MEN1KMT2AALDH1A1SMN1; SMN2GAA
SCHEMBL18550668 0.82 GAA (0.49) MEN1KMT2AALDH1A1SMN1; SMN2GAA
SCHEMBL24356413 0.82 SMN1; SMN2 (0.59) MEN1KMT2AALDH1A1SMN1; SMN2GAA
SCHEMBL23797877 0.82 SMN1; SMN2 (0.59) MEN1KMT2AALDH1A1SMN1; SMN2GAA
SCHEMBL6929125 0.81 GAA (0.70) ALDH1A1SMN1; SMN2GAARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115449136-B Accelerator composition of rubber nanocomposite as well as preparation method and application thereof 浙江大学 2024-02-27 CN claimed
CN-115449136-A Accelerator composition of rubber nanocomposite and preparation method and application thereof 浙江大学 2022-12-09 CN claimed
CN-112946157-A Application of fluorescent thiourea derivatization reagent in 3-chloro-1, 2-propanediol detection 武汉轻工大学 2021-06-11 CN claimed
CN-115449136-B Accelerator composition of rubber nanocomposite as well as preparation method and application thereof 浙江大学 2024-02-27 CN disclosed
EP-2970176-B1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2023-10-25 EP disclosed
US-20230320941-A1 DENTAL COMPOSITION, KIT AND METHOD FOR USE AS ALTERNATIVE RESTORATIVE MATERIAL TO DENTAL AMALGAM SDI LIMITED (AU) 2023-10-12 US disclosed
CN-116600766-A Dental composition, kit and method for use as restorative material for replacement of dental amalgam SDI有限公司 2023-08-15 CN disclosed
EP-4196077-A1 DENTAL COMPOSITION, KIT AND METHOD FOR USE AS ALTERNATIVE RESTORATIVE MATERIAL TO DENTAL AMALGAM Sdi Limited (AU) 2023-06-21 EP disclosed
CN-115449136-A Accelerator composition of rubber nanocomposite and preparation method and application thereof 浙江大学 2022-12-09 CN disclosed
WO-2022032351-A1 DENTAL COMPOSITION, KIT AND METHOD FOR USE AS ALTERNATIVE RESTORATIVE MATERIAL TO DENTAL AMALGAM SDI LIMITED (AU) 2022-02-17 WO disclosed
CN-108369222-B Opioid receptor modulators and uses thereof 明尼苏达大学董事会 2021-06-04 CN disclosed
EP-0397511-A2 Novel cephalosporin compounds and processes for preparation thereof LUCKY, LTD. (KR) 1990-11-14 EP disclosed
US-4816235-A Silver and manganese recovery using acidified thiourea PESIC BATRIC (US) 1989-03-28 US disclosed
US-4778519-A Recovery of precious metals from a thiourea leach PESIC BATRIC (US) 1988-10-18 US disclosed
EP-0000640-B1 TETRAHYDRO-S-TRIAZINE THIONES, PROCESS FOR THEIR PREPARATION AND ACARICIDAL COMPOSITIONS CONTAINING THEM. Pfizer Limited (GB) 1981-06-03 EP disclosed
US-4193994-A ACARICIDES PFIZER INC. (US) 1980-03-18 US disclosed
US-4148799-A Process for the preparation of 2-aryliminothiazoline solutions BAYER AKTIENGESELLSCHAFT (DE) 1979-04-10 US disclosed
EP-0000640-A1 Tetrahydro-s-triazine thiones, process for their preparation and acaricidal compositions containing them. Pfizer Limited (GB) 1979-02-07 EP disclosed
US-3994719-A Resins for separating heavy metals consisting of thiourea-group-containing macroporous vinyl aromatic crosslinked matrixes BAYER AKTIENGESELLSCHAFT (DT) 1976-11-30 US disclosed
US-3991008-A METHACRYLATE MONOMER, HYDROPEROXIDE OXIDIZER, THIOUREA REDUCING AGENT THE KENDALL COMPANY (US) 1976-11-09 US disclosed