Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD3 | Q15059 | 10/20 | 0.67 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | DHODH | Q02127 | 1/20 | 0.51 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459706 | 0.90 | BRD3 (0.59) | BRD3PRMT5GAACASP6SIRT1 | |
| SCHEMBL4021476 | 0.89 | SIRT1 (0.61) | BRD3PRMT5GAACASP6SIRT1 | |
| SCHEMBL5450144 | 0.89 | BRD3 (0.63) | BRD3PRMT5GAACASP6SIRT1 | |
| SCHEMBL4025091 | 0.88 | BRD3 (0.64) | BRD3PRMT5MAPTALOX15MAPK1 | |
| SCHEMBL21114861 | 0.88 | BRD3 (0.64) | BRD3PRMT5MAPTALOX15MAPK1 | |
| SCHEMBL5452182 | 0.87 | GAA (0.55) | BRD3PRMT5GAACASP6SIRT1 | |
| SCHEMBL5445807 | 0.86 | GAA (0.61) | BRD3PRMT5GAACASP6SIRT1 | |
| SCHEMBL5456630 | 0.86 | BRD3 (0.54) | BRD3PRMT5GAACASP6SIRT1 | |
| SCHEMBL4026169 | 0.85 | CYP2D6 (0.56) | BRD3PRMT5GAACASP6SIRT1 | |
| SCHEMBL5456596 | 0.84 | BRD3 (0.59) | BRD3PRMT5GAACASP6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276009-A1 | Compositions and Methods for Viral Inhibition | CHIRON CORPORATION | 2007-11-29 | — | — | US | disclosed |
| US-20070276009-A1 | Compositions and Methods for Viral Inhibition | CHIRON CORPORATION | 2007-11-29 | — | — | US | disclosed |
| US-20070276009-A1 | Compositions and Methods for Viral Inhibition | CHIRON CORPORATION | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276009-A1 | Compositions and Methods for Viral Inhibition | MAVS, SARS1, ZC3HAV1 | BRD3 529/4885PRMT5 1060/4885GAA 1417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.