SCHEMBL545453

SCHEMBL545453

C=C(C)C(=O)OC(C)N(C)C.CCOS(=O)(=O)O

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL134685 0.85 TSHR (0.38) TSHR
Sulfuric Acid SCHEMBL27639849 0.85 TSHR (0.38) TSHR
SCHEMBL28478534 0.84 TSHR (0.39) TSHRTHRB
SCHEMBL127613 0.84 ALDH1A1 (0.38) TSHR
Propane SCHEMBL28466784 0.84 TSHR (0.44) TSHRTHRB
Ammonia Solution, Strong SCHEMBL28986899 0.83 ALDH1A1 (0.36) TSHR
Ether SCHEMBL4069600 0.82 THRB (0.46) TSHRTHRB
Butane SCHEMBL1997610 0.82 TSHR (0.42) TSHRTHRB
SCHEMBL14678050 0.82 TSHR (0.35) TSHRTHRB
SCHEMBL14983 0.82 TSHR (0.43) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130324441-A1 Drilling Fluids Useful For Limiting Tar Sand Accretion DIVERSITY TECHNOLOGIES CORPORATION (CA) 2013-12-05 US claimed
US-7625462-B2 Agent having \"triggerable\" isocyanate bonding functionality blended with papermaking fibers prior to formation of tissue web; after web is dewatered, and during or after drying, triggerable bonding functionality is activated to strengthen resulting sheet structure KIMBERLY-CLARK WORLDWIDE, INC. (US) 2009-12-01 US claimed
US-20070246180-A1 Tissue products containing triggerable polymeric bonding agents KIMBERLY-CLARK WORLDWIDE, INC. 2007-10-25 US claimed
US-9017652-B1 Combination of crosslinked cationic and ampholytic polymers for personal and household applications LUBRIZOL ADVANCED MATERIALS, INC. (US) 2015-04-28 US disclosed
US-20130324441-A1 Drilling Fluids Useful For Limiting Tar Sand Accretion DIVERSITY TECHNOLOGIES CORPORATION (CA) 2013-12-05 US disclosed
CN-102153990-B Polishing liquid composition KAO CORP 2013-08-21 CN disclosed
US-8110013-B2 Polishing composition KAO CORPORATION (JP) 2012-02-07 US disclosed
CN-101139446-B Polishing composition KAO CORP 2011-11-16 CN disclosed
US-8012224-B2 Polishing composition KAO CORPORATION (JP) 2011-09-06 US disclosed
CN-102153990-A Polishing liquid composition KAO CORP 2011-08-17 CN disclosed
US-20110059683-A1 POLISHING COMPOSITION SUZUKI MASAHIKO 2011-03-10 US disclosed
US-7625462-B2 Agent having \"triggerable\" isocyanate bonding functionality blended with papermaking fibers prior to formation of tissue web; after web is dewatered, and during or after drying, triggerable bonding functionality is activated to strengthen resulting sheet structure KIMBERLY-CLARK WORLDWIDE, INC. (US) 2009-12-01 US disclosed
US-20080115422-A1 Polishing composition KAO CORPORATION (JP) 2008-05-22 US disclosed
CN-101139446-A Polishing composition KAO CORP (JP) 2008-03-12 CN disclosed
US-20070246180-A1 Tissue products containing triggerable polymeric bonding agents KIMBERLY-CLARK WORLDWIDE, INC. 2007-10-25 US disclosed
US-5830844-A WATER INSOLUBLE CROSSLINKED POLYMERS CONTAINING PYRROLIDONE AND IMIDAZOLE RINGS BASF AKTIENGESELLSCHAFT (DE) 1998-11-03 US disclosed