SCHEMBL5454572

SCHEMBL5454572

CC(=O)NC(=O)C[C@@H](N)[C]=O

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.36
TAS2R38 P59533 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11557958 1.00 CRBN (0.36) CRBNTAS2R38
SCHEMBL11363509 0.80 CYP2D6 (0.34) CRBNTAS2R38
SCHEMBL11345209 0.78
SCHEMBL8353811 0.72 GRIK1 (0.50)
SCHEMBL14344224 0.72 GRIK1 (0.50)
SCHEMBL22769505 0.72 GRIK1 (0.50)
SCHEMBL9438438 0.71 GRIK1 (0.48)
SCHEMBL18057552 0.70 ALDH1A1 (0.50)
SCHEMBL18766394 0.70 ALDH1A1 (0.38) CRBNTAS2R38
SCHEMBL10404787 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070010655-A1 Stationary phases and a purification process using the stationary phases MERCK & CO., INC. 2007-01-11 US disclosed
EP-1663275-A2 STATIONARY PHASES AND A PURIFICATION PROCESS USING THE STATIONARY PHASES Merck & Co., Inc. (US) 2006-06-07 EP disclosed
WO-2005026323-A2 STATIONARY PHASES AND A PURIFICATION PROCESS USING THE STATIONARY PHASES MERCK & CO., INC. (US) 2005-03-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070010655-A1 Stationary phases and a purification process using the stationary phases VIP, LPXN, PROKR1 CRBN 4321/4885TAS2R38 2570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.