Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 9/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8353811 | 0.98 | GRIK1 (0.50) | GRIK1SLC7A5GRIK2GRM1GRM2 | |
| SCHEMBL22769505 | 0.98 | GRIK1 (0.50) | GRIK1SLC7A5GRIK2GRM1GRM2 | |
| SCHEMBL14344224 | 0.98 | GRIK1 (0.50) | GRIK1SLC7A5GRIK2GRM1GRM2 | |
| SCHEMBL8176334 | 0.79 | GRIK1 (0.47) | GRIK1SLC7A5GRIK2GRM1GRM2 | |
| SCHEMBL467809 | 0.78 | GRM8 (0.54) | GRIK1GRIK2GRM1GRM2GRIA4 | |
| SCHEMBL2909135 | 0.78 | GRM8 (0.54) | GRIK1GRIK2GRM1GRM2GRIA4 | |
| SCHEMBL369357 | 0.77 | GRIK1 (0.48) | GRIK1SLC7A5GRIK2GRM1GRM2 | |
| SCHEMBL8160588 | 0.76 | GRM8 (0.52) | GRIK1GRIK2GRM1GRM2GRIA4 | |
| SCHEMBL359673 | 0.76 | SLC7A5 (0.50) | GRIK1SLC7A5GRIK2GRM1GRM2 | |
| SCHEMBL8368782 | 0.76 | SLC7A5 (0.50) | GRIK1SLC7A5GRIK2GRM1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358705-A | For reducing or preventing dental plaque or oral diseases, dentifrices, mouthwashes | THE PROCTER & GAMBLE COMPANY (US) | 1994-10-25 | — | — | US | disclosed |
| US-5286480-A | Reducing dental plaque coating on teeth | THE PROCTER & GAMBLE COMPANY (US) | 1994-02-15 | — | — | US | disclosed |