Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GHSR | Q92847 | 5/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5454943 | 0.84 | MAPT (0.59) | HRH3ALDH1A1DRD3HTR6DRD2 | |
| SCHEMBL5451236 | 0.81 | L3MBTL1 (0.50) | HRH3ALDH1A1DRD3HTR6DRD2 | |
| SCHEMBL5466214 | 0.81 | KMT2A (0.42) | HRH3DRD3HTR6DRD2KMT2A | |
| SCHEMBL5458294 | 0.81 | TMEM97 (0.45) | HRH3ALDH1A1DRD3HTR6DRD2 | |
| SCHEMBL5454888 | 0.78 | MEN1 (0.55) | HRH3ALDH1A1DRD3HTR6DRD2 | |
| SCHEMBL5458846 | 0.78 | HRH3 (0.74) | HRH3ALDH1A1DRD3HTR6DRD2 | |
| SCHEMBL5465985 | 0.76 | ALDH1A1 (0.60) | HRH3ALDH1A1KMT2AL3MBTL1MAPT | |
| SCHEMBL5461526 | 0.75 | HRH3 (0.55) | HRH3ALDH1A1DRD3HTR6DRD2 | |
| SCHEMBL5466147 | 0.75 | HRH3 (0.46) | HRH3ALDH1A1DRD3HTR6DRD2 | |
| SCHEMBL5458924 | 0.75 | HRH3 (0.66) | HRH3ALDH1A1DRD3HTR6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185089-A1 | Benzazepine derivatives for the treatment of neurological and psychiatric disorders | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185089-A1 | Benzazepine derivatives for the treatment of neurological and psychiatric disorders | CNR2, GRIN2C, GRIN2B | HRH3 38/4885ALDH1A1 1805/4885DRD3 104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.