SCHEMBL5454920

SCHEMBL5454920

COc1ccc(CNC(=S)Nc2ccccc2)cc1OC

nearest known ligand 0.79

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.79
MEN1 O00255 7/20 0.79
MAOB P27338 3/20 0.60
MAOA P21397 1/20 0.60
POLB P06746 1/20 0.60
QPCT Q16769 1/20 0.60
MAPT P10636 2/20 0.59
LMNA P02545 1/20 0.58
ALDH1A1 P00352 2/20 0.57
HPGD P15428 1/20 0.57
ALOX12 P18054 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11034358 0.89 MEN1 (0.71) KMT2AMEN1QPCT
SCHEMBL22289851 0.86 MAPT (0.74) KMT2AMEN1MAOBMAOAMAPT
SCHEMBL85941 0.86 MAOB (0.68) KMT2AMEN1MAOBMAOAPOLB
SCHEMBL27953132 0.83 ALDH1A1 (0.73) KMT2AMEN1MAOBPOLBQPCT
SCHEMBL5450386 0.81 MAOB (0.89) KMT2AMEN1MAOBMAOAPOLB
SCHEMBL5313746 0.81 GAA (0.81) KMT2APOLBMAPTLMNAALDH1A1
SCHEMBL30388749 0.79 MAOB (0.83) KMT2AMEN1MAOBMAOAPOLB
SCHEMBL8615025 0.78 MAPT (0.67) KMT2AMEN1MAOBMAOAPOLB
SCHEMBL4861526 0.77 MAPT (0.74) KMT2AMEN1POLBMAPTLMNA
SCHEMBL6676537 0.77 KMT2A (0.71) KMT2AMEN1POLBMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101129295-B There is the binary initiator system of good storage stability and especially suitable for acidic system HERAEUS KULZER GMBH (DE) 2016-02-10 CN disclosed
CN-101129295-A 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems HERAEUS KULZER GMBH (DE) 2008-02-27 CN disclosed
US-20070040151-A1 Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems HERAEUS KULZER GMBH (DE) 2007-02-22 US disclosed