Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.81 |
| ▸ | LMNA | P02545 | 3/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | BCHE | P06276 | 2/20 | 0.60 |
| ▸ | ACHE | P22303 | 2/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL604694 | 0.88 | GAA (0.68) | GAAALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL3653095 | 0.86 | EPHX2 (0.77) | ALDH1A1LMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL5454920 | 0.81 | KMT2A (0.79) | ALDH1A1LMNAKMT2AMAPTHPGD | |
| SCHEMBL3808723 | 0.80 | GAA (1.00) | GAAALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL22289851 | 0.79 | MAPT (0.74) | GAAALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL28020357 | 0.77 | BCHE (0.68) | ALDH1A1LMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL13979988 | 0.76 | NPSR1 (0.59) | GAAALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL28618230 | 0.75 | CHEK1 (0.63) | GAAALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL11275576 | 0.74 | KMT2A (0.67) | ALDH1A1LMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL1645810 | 0.74 | KMT2A (0.71) | GAAALDH1A1LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |