Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.30 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.30 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | GPR183 | P32249 | 1/20 | 0.30 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tromethamine SCHEMBL28419666 | 0.80 | LMNA (0.46) | LMNAMEN1KMT2ASLC6A6CYP2C19 | |
| Tromethamine SCHEMBL6064575 | 0.79 | LMNA (0.56) | LMNAMEN1KMT2ASLC6A6CYP2C19 | |
| SCHEMBL20873468 | 0.77 | LMNA (0.40) | LMNAMEN1KMT2ASLC6A6CYP2C19 | |
| SCHEMBL6771786 | 0.76 | LMNA (0.39) | LMNASLC6A6CYP2C19BLMAPP | |
| SCHEMBL1326231 | 0.76 | S1PR1 (0.39) | LMNASLC6A6CYP2C19BLMAPP | |
| SCHEMBL26305886 | 0.76 | PTGS1 (0.33) | LMNASLC6A6CYP2C19BLMAPP | |
| SCHEMBL6766541 | 0.74 | PTGS1 (0.37) | LMNASLC6A6CYP2C19BLMAPP | |
| SCHEMBL1131443 | 0.74 | — | — | |
| SCHEMBL1117318 | 0.74 | — | — | |
| SCHEMBL23001184 | 0.74 | S1PR1 (0.45) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179357-B2 | Serial sample injection in capillary electrophoresis | BECKMAN COULTER, INC. (US) | 2007-02-20 | — | — | US | disclosed |
| US-20040079640-A1 | Serial sample injection in capillary electrophoresis | BECKMAN COULTER, INC. | 2004-04-29 | — | — | US | disclosed |