Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Urethane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urethane SCHEMBL15486414 | 1.00 | ALOX15 (0.79) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| Urethane SCHEMBL11065884 | 0.97 | ALOX15 (0.75) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| Urethane SCHEMBL11065868 | 0.97 | ALOX15 (0.75) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| Urethane SCHEMBL28033851 | 0.90 | ALOX15 (0.71) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| Urethane SCHEMBL10973781 | 0.90 | ALOX15 (0.71) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| Urethane SCHEMBL28033850 | 0.90 | ALOX15 (0.71) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| Urethane SCHEMBL8830978 | 0.89 | ALOX15 (1.00) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| Urethane SCHEMBL8136 | 0.89 | — | — | |
| Urethane SCHEMBL8505249 | 0.89 | ALOX15 (1.00) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| Urethane SCHEMBL367439 | 0.89 | ALOX15 (1.00) | ALOX15ALDH1A1LMNAHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110917909-B | Method for preparing separation membrane by using poly (amino) sulfate polymer and modified polymer thereof as membrane preparation material | 乌海图微新材料科技有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-113896891-A | Method for end-capping modified poly (amino) sulfate | 白银图微新材料科技有限公司 | 2022-01-07 | — | — | CN | claimed |
| CN-112495198-A | Technology for preparing film by using poly (amino) sulfate polymer and application | 白银图微新材料科技有限公司 | 2021-03-16 | — | — | CN | claimed |
| CN-111116914-A | Synthesis method for preparing sulfonated poly (amino) sulfate by using poly (amino) sulfate polymer as raw material | 白银图微新材料科技有限公司 | 2020-05-08 | — | — | CN | claimed |
| CN-110917909-A | Method for preparing separation membrane by using poly (amino) sulfate polymer and modified polymer thereof as membrane preparation material | 白银图微新材料科技有限公司 | 2020-03-27 | — | — | CN | claimed |
| CN-119731153-A | Method for producing polythiol composition, method for producing polyamine compound, and use thereof | 三井化学株式会社 | 2025-03-28 | — | — | CN | disclosed |
| CN-115943139-B | Method for producing thiourethane resin raw material and use thereof | 三井化学株式会社 | 2025-02-14 | — | — | CN | disclosed |
| CN-118510824-A | Method for producing polythiol composition, composition control system for thiourethane resin raw material, and use thereof | 三井化学株式会社 | 2024-08-16 | — | — | CN | disclosed |
| CN-117181017-A | Crosslinked polyamide gas separation membrane and preparation method and application thereof | 北京瑞实气体分离技术有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-117101443-A | Cross-linked polysulfonamide gas separation membrane and preparation method and application thereof | 北京瑞实气体分离技术有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-110540647-B | Polymerization method of sulfuric acid (amine) ester connector polymer | 内蒙古图微新材料科技有限公司 | 2023-09-29 | — | — | CN | disclosed |
| WO-2022148442-A1 | 6-SUBSTITUTED PHOSPHORYL QUINAZOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-07-14 | — | — | WO | disclosed |
| CN-102304853-A | Polyether polyurethane sulfate anionic macromolecular surfactant and preparation method and application thereof | SHANGHAI INST ORGANIC CHEM | 2012-01-04 | — | — | CN | disclosed |
| CN-102304853-A | Polyether polyurethane sulfate anionic macromolecular surfactant and preparation method and application thereof | SHANGHAI INST ORGANIC CHEM | 2012-01-04 | — | — | CN | disclosed |
| CN-102304853-A | Polyether polyurethane sulfate anionic macromolecular surfactant and preparation method and application thereof | SHANGHAI INST ORGANIC CHEM | 2012-01-04 | — | — | CN | disclosed |
| US-7253152-B2 | Electrically conductive polymeric biomaterials, the process for their preparation and the use thereof in the biomedical and healthcare field | FIDIA ADVANCED BIOPOLYMERS S.R.L. (IT) | 2007-08-07 | — | — | US | disclosed |
| EP-1390088-B1 | ELECTRICALLY CONDUCTIVE POLYMERIC BIOMATERIALS, THE PROCESS FOR THEIR PREPARATION AND THE USE THEREOF IN THE BIOMEDICAL AND HEALTHCARE FIELD | FIDIA ADVANCED BIOPOLYMERS SRL (IT) | 2005-12-21 | — | — | EP | disclosed |
| US-20040131651-A1 | Electrically conductive polymeric biomaterials, the process for their preparation and the use thereof in the biomedical and healthcare field | ANIKA THERAPEUTICS S.R.L. (IT) | 2004-07-08 | — | — | US | disclosed |
| EP-1390088-A2 | ELECTRICALLY CONDUCTIVE POLYMERIC BIOMATERIALS, THE PROCESS FOR THEIR PREPARATION AND THE USE THEREOF IN THE BIOMEDICAL AND HEALTHCARE FIELD | FIDIA ADVANCED BIOPOLYMERS S.R.L. (IT) | 2004-02-25 | — | — | EP | disclosed |
| WO-2003000309-A2 | ELECTRICALLY CONDUCTIVE POLYMERIC BIOMATERIALS, THE PROCESS FOR THEIR PREPARATION AND THE USE THEREOF IN THE BIOMEDICAL AND HEALTHCARE FIELD | FIDIA ADVANCED BIOPOLYMERS S.R.L. (IT) | 2003-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040131651-A1 | Electrically conductive polymeric biomaterials, the process for their preparation and the use thereof in the biomedical and healthcare field | CD44, GYPA, HPSE | CHRM2 3153/4885CHRM1 3818/4885CHRM3 2459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.