Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GUSB | P08236 | 6/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449392 | 0.77 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10KMT2AGUSB | |
| SCHEMBL5455181 | 0.77 | ALDH1A1 (0.53) | KDM4EALDH1A1HSD17B10KMT2AGUSB | |
| SCHEMBL24278256 | 0.73 | ALDH1A1 (0.57) | KDM4EALDH1A1HSD17B10KMT2AGUSB | |
| SCHEMBL5447135 | 0.73 | ALDH1A1 (0.51) | KDM4EALDH1A1HSD17B10KMT2AGUSB | |
| SCHEMBL5455177 | 0.71 | KDM4E (0.52) | KDM4EALDH1A1HSD17B10KMT2AGUSB | |
| SCHEMBL3629921 | 0.71 | ALDH1A1 (0.47) | KDM4EALDH1A1HSD17B10KMT2AGUSB | |
| SCHEMBL20800911 | 0.69 | TAAR1 (0.65) | KDM4EALDH1A1HSD17B10KMT2AGUSB | |
| SCHEMBL20798352 | 0.68 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10KMT2AGUSB | |
| SCHEMBL5453511 | 0.68 | HSD17B10 (0.52) | KDM4EALDH1A1HSD17B10KMT2AGUSB | |
| SCHEMBL21549811 | 0.66 | KDM4E (0.40) | KDM4EALDH1A1HSD17B10KMT2AGUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287706-A1 | Certain substituted quinolones, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287706-A1 | Certain substituted quinolones, compositions, and uses thereof | ABCG2, ATP5ME, ATP5MG | KDM4E 2403/4885ALDH1A1 1055/4885HSD17B10 1580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.