Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | ATF1 | P18846 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1014805 | 0.82 | ALDH1A1 (0.55) | KDM4EALDH1A1HSD11B1PTPN11PIK3CB | |
| SCHEMBL6925687 | 0.80 | HCRTR1 (0.56) | CNR2KDM4EALDH1A1LMNAPKM | |
| SCHEMBL1837114 | 0.80 | KDM4E (0.53) | CNR2KDM4EALDH1A1LMNAPKM | |
| SCHEMBL12796003 | 0.78 | ALDH1A1 (0.58) | CNR2KDM4EALDH1A1LMNAPKM | |
| SCHEMBL1014459 | 0.76 | HSD11B1 (0.58) | KDM4EALDH1A1HSD11B1PTPN11PIK3CB | |
| SCHEMBL1015481 | 0.76 | HSD11B1 (0.58) | KDM4EALDH1A1HSD11B1PTPN11PIK3CB | |
| SCHEMBL1012134 | 0.76 | KDM4E (0.58) | CNR2KDM4EALDH1A1LMNAPKM | |
| SCHEMBL10327933 | 0.76 | PIK3CA (0.56) | PTPN11PIK3CBPIK3R1PIK3CAMTOR | |
| SCHEMBL19145299 | 0.76 | KDM4E (0.51) | CNR2KDM4EALDH1A1PIK3CBPIK3R1 | |
| SCHEMBL12795989 | 0.76 | KDM4E (0.54) | CNR2KDM4EALDH1A1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259849-A1 | Azine-Carboxamides as Anti-Cancer Agents | ASTRAZENECA AB (SE) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259849-A1 | Azine-Carboxamides as Anti-Cancer Agents | ARAF, BRAF, RAF1 | CNR2 991/4885KDM4E 521/4885ALDH1A1 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.