Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.47 |
| ▸ | BTN3A1 | O00481 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MVD | P53602 | 2/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | ITPR3 | Q14573 | 1/20 | 0.39 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL379135 | 0.89 | LPAR3 (0.57) | LPAR3LPAR1LPAR2BTN3A1CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL28249850 | 0.87 | LPAR3 (0.55) | LPAR3LPAR1LPAR2BTN3A1CYP3A4 | |
| Di(Hydroxyethyl)Ether SCHEMBL21694831 | 0.86 | TSHR (0.53) | LPAR3LPAR1LPAR2BTN3A1CYP3A4 | |
| Monoethanolamine SCHEMBL5459834 | 0.86 | CYP3A4 (0.53) | LPAR3LPAR1LPAR2CYP3A4GABBR2 | |
| SCHEMBL18798621 | 0.85 | LPAR3 (0.53) | LPAR3LPAR1LPAR2BTN3A1CYP3A4 | |
| SCHEMBL10935345 | 0.85 | LPAR3 (0.53) | LPAR3LPAR1LPAR2BTN3A1CYP3A4 | |
| SCHEMBL2869539 | 0.83 | LPAR3 (0.67) | LPAR3LPAR1LPAR2BTN3A1CYP3A4 | |
| SCHEMBL5705550 | 0.82 | LPAR3 (0.50) | LPAR3LPAR1LPAR2BTN3A1CYP3A4 | |
| Monoethanolamine SCHEMBL30909389 | 0.82 | LPAR3 (0.60) | LPAR3LPAR1LPAR2 | |
| Monoethanolamine SCHEMBL10715779 | 0.82 | LPAR3 (0.60) | LPAR3LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070210476-A1 | Machinable Resin Molded Product, Material For Forming The Same, And Model Made Of The Same | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
| EP-1728832-A1 | MOLDING OF RESIN FOR CUTTING OPERATION, MATERIAL FOR FORMATION THEREOF AND MODEL | Sanyo Chemical Industries, Ltd. (JP) | 2006-12-06 | — | — | EP | disclosed |