Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455710 | 1.00 | HSD11B1 (0.60) | HSD11B1ALDH1A1 | |
| SCHEMBL2793564 | 0.79 | HSD11B1 (0.50) | HSD11B1ALDH1A1 | |
| SCHEMBL350965 | 0.78 | HSD11B1 (0.66) | HSD11B1 | |
| SCHEMBL349516 | 0.78 | HSD11B1 (0.66) | HSD11B1 | |
| SCHEMBL348724 | 0.75 | HSD11B1 (1.00) | HSD11B1ALDH1A1 | |
| SCHEMBL2796409 | 0.75 | CYP2D6 (0.49) | HSD11B1ALDH1A1 | |
| SCHEMBL18390053 | 0.75 | HSD11B1 (0.74) | HSD11B1ALDH1A1 | |
| SCHEMBL347591 | 0.74 | HSD11B1 (0.68) | HSD11B1ALDH1A1 | |
| SCHEMBL351015 | 0.74 | HSD11B1 (0.68) | HSD11B1ALDH1A1 | |
| SCHEMBL348770 | 0.73 | HSD11B1 (0.88) | HSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007137098-A2 | SULFONYL-SUBSTITUTED BICYCLIC COMPOUNDS AS MODULATORS OF PPAR | KALYPSYS, INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| US-20070270434-A1 | SULFONYL-SUBSTITUTED BICYCLIC COMPOUNDS AS MODULATORS OF PPAR | KALYPSYS, INC. (US) | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270434-A1 | SULFONYL-SUBSTITUTED BICYCLIC COMPOUNDS AS MODULATORS OF PPAR | PPARD, PPARG, PPARA | HSD11B1 658/4885ALDH1A1 1775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.