Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 18/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351050 | 0.93 | HSD11B1 (1.00) | HSD11B1ALDH1A1MEN1KMT2A | |
| SCHEMBL350439 | 0.93 | HSD11B1 (1.00) | HSD11B1ALDH1A1MEN1KMT2A | |
| SCHEMBL18390053 | 0.85 | HSD11B1 (0.74) | HSD11B1ALDH1A1 | |
| SCHEMBL349696 | 0.84 | HSD11B1 (0.74) | HSD11B1ALDH1A1 | |
| SCHEMBL350767 | 0.83 | HSD11B1 (0.70) | HSD11B1ALDH1A1 | |
| SCHEMBL3139523 | 0.83 | HSD11B1 (0.71) | HSD11B1ALDH1A1MEN1KMT2A | |
| SCHEMBL3129900 | 0.82 | HSD11B1 (1.00) | HSD11B1ALDH1A1MEN1KMT2A | |
| SCHEMBL20315431 | 0.82 | HSD11B1 (0.68) | HSD11B1ALDH1A1 | |
| SCHEMBL18390057 | 0.82 | HSD11B1 (0.68) | HSD11B1ALDH1A1 | |
| SCHEMBL3447152 | 0.82 | HSD11B1 (0.74) | HSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2963021-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Holdings Corporation (US) | 2016-01-06 | — | — | EP | claimed |
| US-20150329561-A1 | Amido Compounds And Their Use As Pharmaceuticals | INCYTE CORPORATION | 2015-11-19 | — | — | US | claimed |
| US-20120015928-A1 | Amido Compounds And Their Use As Pharmaceuticals | INCYTE CORPORATION (US) | 2012-01-19 | — | — | US | claimed |
| US-20100256114-A1 | Amido Compounds And Their Use As Pharmaceuticals | INCYTE CORPORATION (US) | 2010-10-07 | — | — | US | claimed |
| US-20070179142-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2007-08-02 | — | — | US | claimed |
| US-20050282858-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2005-12-22 | — | — | US | claimed |
| US-9957229-B2 | Amido compounds and their use as pharmaceuticals | INCYTE HOLDINGS CORPORATION (US) | 2018-05-01 | — | — | US | disclosed |
| US-20170334847-A1 | Amido Compounds And Their Use As Pharmaceuticals | INCYTE CORPORATION | 2017-11-23 | — | — | US | disclosed |
| US-9670154-B2 | Amido compounds and their use as pharmaceuticals | INCYTE HOLDINGS CORPORATION (US) | 2017-06-06 | — | — | US | disclosed |
| EP-2963021-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Holdings Corporation (US) | 2016-01-06 | — | — | EP | disclosed |
| US-20150329561-A1 | Amido Compounds And Their Use As Pharmaceuticals | INCYTE CORPORATION | 2015-11-19 | — | — | US | disclosed |
| US-9126927-B2 | Amido compounds and their use as pharmaceuticals | INCYTE HOLDINGS CORPORATION (US) | 2015-09-08 | — | — | US | disclosed |
| EP-1756063-B1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2015-07-08 | — | — | EP | disclosed |
| US-20050282858-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2005-12-22 | — | — | US | disclosed |
| US-20050040074-A1 | Hydrocarbon conversion using molecular sieve SSZ-65 | CHEVRON U.S.A. INC. | 2005-02-24 | — | — | US | disclosed |
| US-20050042159-A1 | Using molecular sieve SSZ-65 for reduction of oxides of nitrogen in a gas stream | CHEVRON U.S.A. INC. | 2005-02-24 | — | — | US | disclosed |
| US-20050042169-A1 | Molecular sieve SSZ-65 composition of matter and synthesis thereof | CHEVRON U.S.A. INC. | 2005-02-24 | — | — | US | disclosed |
| US-20040187684-A1 | Using molecular sieve SSZ-65 for reduction of oxides of nitrogen in a gas stream | CHEVRON U.S.A. INC. | 2004-09-30 | — | — | US | disclosed |
| US-20040191167-A1 | Zeolite SSZ-65 composition of matter and synthesis thereof utility | CHEVRON U.S.A. INC. | 2004-09-30 | — | — | US | disclosed |
| US-20040188324-A1 | Hydrocarbon conversion using molecular sieve SSZ-65 | CHEVRON U.S.A. INC. | 2004-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334847-A1 | Amido Compounds And Their Use As Pharmaceuticals | HSD11B1, CYP11B1, HSD11B2 | HSD11B1 1/4885ALDH1A1 311/4885MEN1 379/4885 |
| US-20050040074-A1 | Hydrocarbon conversion using molecular sieve SSZ-65 | SRP72, SSU72, SRP68 | HSD11B1 1475/4885ALDH1A1 3603/4885MEN1 3947/4885 |
| US-20100256114-A1 | Amido Compounds And Their Use As Pharmaceuticals | HSD11B1, CYP11B1, HSD11B2 | HSD11B1 1/4885ALDH1A1 311/4885MEN1 379/4885 |
| US-20050282858-A1 | Amido compounds and their use as pharmaceuticals | HSD11B1, CYP11B1, HSD11B2 | HSD11B1 1/4885ALDH1A1 311/4885MEN1 379/4885 |
| US-20120015928-A1 | Amido Compounds And Their Use As Pharmaceuticals | HSD11B1, CYP11B1, HSD11B2 | HSD11B1 1/4885ALDH1A1 311/4885MEN1 379/4885 |
| US-20040188324-A1 | Hydrocarbon conversion using molecular sieve SSZ-65 | SRP72, SSU72, SRP68 | HSD11B1 1459/4885ALDH1A1 3604/4885MEN1 3912/4885 |
| US-20150329561-A1 | Amido Compounds And Their Use As Pharmaceuticals | HSD11B1, CYP11B1, HSD11B2 | HSD11B1 1/4885ALDH1A1 311/4885MEN1 379/4885 |
| US-20070179142-A1 | Amido compounds and their use as pharmaceuticals | HSD11B1, CYP11B1, HSD11B2 | HSD11B1 1/4885ALDH1A1 311/4885MEN1 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.