Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.76 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | FLT3 | P36888 | 8/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CFTR | P13569 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469940 | 0.91 | MAPT (0.79) | MAPTALDH1A1GAAFLT3NPC1 | |
| SCHEMBL15199363 | 0.88 | ALDH1A1 (0.80) | MAPTALDH1A1GAAFLT3NPC1 | |
| SCHEMBL12469817 | 0.84 | ALDH1A1 (1.00) | MAPTALDH1A1GAAKMT2AMEN1 | |
| Benzene SCHEMBL5455893 | 0.80 | ALDH1A1 (0.67) | MAPTALDH1A1GAAFLT3NPC1 | |
| SCHEMBL5453222 | 0.79 | FLT3 (1.00) | MAPTALDH1A1FLT3NPC1RAB9A | |
| SCHEMBL5453363 | 0.77 | FLT3 (0.71) | MAPTALDH1A1GAAFLT3NPC1 | |
| SCHEMBL8290726 | 0.77 | FLT3 (1.00) | MAPTALDH1A1GAAFLT3NPC1 | |
| SCHEMBL12632694 | 0.76 | FLT3 (0.98) | MAPTALDH1A1GAAFLT3NPC1 | |
| SCHEMBL5460093 | 0.75 | FLT3 (0.87) | MAPTALDH1A1GAAFLT3NPC1 | |
| SCHEMBL21045428 | 0.74 | FLT3 (0.95) | MAPTALDH1A1GAAFLT3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | claimed |
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | TBCA, PARK7, NFATC1 | MAPT 21/4885ALDH1A1 1153/4885GAA 540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.