Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | GAA | P10253 | 4/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | AR | P10275 | 3/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17654176 | 0.85 | ALDH1A1 (0.79) | ALDH1A1GAAMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL5199794 | 0.81 | ALDH1A1 (0.96) | ALDH1A1GAAMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL11372459 | 0.79 | ALDH1A1 (1.00) | ALDH1A1GAAMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL17654100 | 0.79 | ALDH1A1 (0.84) | ALDH1A1GAAMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL5631018 | 0.79 | ALDH1A1 (1.00) | ALDH1A1GAAMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL25859539 | 0.78 | RAB9A (0.42) | ALDH1A1GAAMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL13428031 | 0.76 | AR (0.44) | ALDH1A1GAAHSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL2397484 | 0.76 | ALDH1A1 (0.66) | ALDH1A1GAAMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL12263529 | 0.76 | PIK3CD (0.46) | ALDH1A1GAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8771166 | 0.74 | SMN1; SMN2 (0.40) | ALDH1A1GAAHSD17B10SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064273-B1 | 1,3,4-THIADIAZOLES USEFUL FOR THE TREATMENT OF CMV INFECTIONS | UPJOHN CO (US) | 2002-12-18 | — | — | EP | claimed |
| EP-2944637-B1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-02-19 | — | — | EP | disclosed |
| CN-104903320-B | Nitrogen-containing heterocycle compound or its salt | 富士胶片株式会社 | 2018-11-13 | — | — | CN | disclosed |
| US-10005769-B2 | 2,3-dihydrobenzofuran-5YL compounds as DYRK kinase inhibitors | 4SC AG (DE) | 2018-06-26 | — | — | US | disclosed |
| US-9783536-B2 | Nitrogen-containing heterocyclic compound or salt thereof | FUJIFILM CORPORATION (JP) | 2017-10-10 | — | — | US | disclosed |
| US-9783536-B2 | Nitrogen-containing heterocyclic compound or salt thereof | FUJIFILM CORPORATION (JP) | 2017-10-10 | — | — | US | disclosed |
| US-9783536-B2 | Nitrogen-containing heterocyclic compound or salt thereof | FUJIFILM CORPORATION (JP) | 2017-10-10 | — | — | US | disclosed |
| US-20160137637-A1 | 2,3-DIHYDROBENZOFURAN-5YL COMPOUNDS AS DYRK KINASE INHIBITORS | 4SC DISCOVERY GMBH (DE) | 2016-05-19 | — | — | US | disclosed |
| EP-3010920-A1 | 2,3-DIHYDROBENZOFURAN-5-YL COMPOUNDS AS DYRK KINASE INHIBITORS | 4SC Discovery GmbH (DE) | 2016-04-27 | — | — | EP | disclosed |
| WO-2014202638-A9 | 2,3-DIHYDROBENZOFURAN-5-YL COMPOUNDS AS DYRK KINASE INHIBITORS | 4SC DISCOVERY GMBH (DE) | 2016-03-03 | — | — | WO | disclosed |
| US-6150385-A | VIRICIDE WITH ACTIVITY AGAINST CYTOMEGALO VIRUS (CMV), HERPES VIRUS INCLUDING VARICELLA ZOSTER VIRUS, THE EPSTEIN-BARR VIRUS, THE HERPES SIMPLEX VIRUS, AND THE HUMAN HERPES VIRUS TYPE 8 (HHV-8) | PHARMACIA & UPJOHN COMPANY (US) | 2000-11-21 | — | — | US | disclosed |
| WO-1999047507-A2 | 1,3,4-THIADIAZOLES USEFUL FOR THE TREATMENT OF CMV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1999-09-23 | — | — | WO | disclosed |
| EP-0567846-B1 | Cationic triazatrimethine dyes | BAYER AG (DE) | 1996-12-04 | — | — | EP | disclosed |
| US-5328993-A | Dyeing plastics; colorfastness, photostability | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |
| EP-0567846-A1 | Cationic triazatrimethine dyes | BAYER AG (DE) | 1993-11-03 | — | — | EP | disclosed |
| EP-0567849-A1 | Process for preparing dyes | BAYER AG (DE) | 1993-11-03 | — | — | EP | disclosed |
| US-4522944-A | ANTIINFLAMMATORY AGENTS AND PAIN KILLERS | FARMITALIA CARLO ERBA S.P.A., MILAN ITALY A CORP OF ITALY (IT) | 1985-06-11 | — | — | US | disclosed |
| US-4500715-A | CHEMICAL INTERMEDIATES FOR PLANT SAFENING AGENTS AND DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-02-19 | — | — | US | disclosed |
| US-4281120-A | IMMUNE STIMULANTS | GRUNENTHAL GMBH (DE) | 1981-07-28 | — | — | US | disclosed |
| US-4268438-A | Cationic 1,3,4-thiadiazole dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10005769-B2 | 2,3-dihydrobenzofuran-5YL compounds as DYRK kinase inhibitors | DYRK2, DYRK1B, DYRK1A | ALDH1A1 2116/4885GAA 2202/4885MAPK1 234/4885 |
| US-20160137637-A1 | 2,3-DIHYDROBENZOFURAN-5YL COMPOUNDS AS DYRK KINASE INHIBITORS | DYRK2, DYRK1B, DYRK1A | ALDH1A1 2116/4885GAA 2202/4885MAPK1 234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.