Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | CPA1 | P15085 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5475631 | 0.92 | ALDH1A1 (0.56) | ALDH1A1MAPTUSP2MEN1KMT2A | |
| SCHEMBL5469924 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MAPTUSP2MEN1KMT2A | |
| SCHEMBL5465310 | 0.82 | RNPEP (0.47) | ALDH1A1MAPTUSP2RNPEPTSHR | |
| SCHEMBL5471497 | 0.79 | RNPEP (0.53) | ALDH1A1MAPTRNPEPLMNAPTGS2 | |
| SCHEMBL5463899 | 0.79 | FNTA (0.44) | RNPEPLMNA | |
| SCHEMBL5470111 | 0.79 | DNM1 (0.41) | ALDH1A1MEN1KMT2ARNPEP | |
| SCHEMBL5469946 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTUSP2MEN1KMT2A | |
| SCHEMBL5471493 | 0.78 | RNPEP (0.42) | ALDH1A1MAPTUSP2MEN1KMT2A | |
| SCHEMBL5469957 | 0.78 | RNPEP (0.50) | ALDH1A1MAPTRNPEPLMNAPTGS2 | |
| SCHEMBL5469541 | 0.75 | ALDH1A1 (0.52) | ALDH1A1MAPTUSP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070009462-A9 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | MALLE GERARD | 2007-01-11 | — | — | US | claimed |
| US-20050201964-A1 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | L'OREAL S.A. (FR) | 2005-09-15 | — | — | US | claimed |
| US-20070009462-A9 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | MALLE GERARD | 2007-01-11 | — | — | US | disclosed |
| US-20050201964-A1 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | L'OREAL S.A. (FR) | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050201964-A1 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | NR5A1, SRD5A2, HRH3 | ALDH1A1 792/4885MAPT 3323/4885USP2 2478/4885 |
| US-20070009462-A9 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | NR5A1, SRD5A2, HRH3 | ALDH1A1 792/4885MAPT 3323/4885USP2 2478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.