Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.60 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5465698 | 0.82 | PRMT5 (0.59) | NOD1CXCL8TP53KMT2AHTT | |
| SCHEMBL5454046 | 0.82 | KMT2A (0.51) | NOD1CXCL8TP53KMT2AHTT | |
| SCHEMBL10025496 | 0.79 | KMT2A (0.80) | NOD1CXCL8TP53KMT2AHTT | |
| SCHEMBL5456433 | 0.77 | PRMT5 (0.56) | NOD1CXCL8TP53KMT2AHTT | |
| SCHEMBL5453935 | 0.75 | TLR8 (0.66) | NOD1HTTPRMT5TNFNOD2 | |
| SCHEMBL5127626 | 0.74 | PRMT5 (0.49) | NOD1CXCL8TP53KMT2AHTT | |
| SCHEMBL5463706 | 0.74 | PRMT5 (0.63) | NOD1CXCL8TP53KMT2AHTT | |
| SCHEMBL20715540 | 0.72 | TP53 (1.00) | NOD1CXCL8TP53KMT2AHTT | |
| SCHEMBL5141398 | 0.72 | PRMT5 (0.56) | NOD1CXCL8TP53KMT2AHTT | |
| SCHEMBL5472851 | 0.71 | PRMT5 (0.48) | NOD1TP53KMT2AHTTPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | ABBOTT LABORATORIES | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | CYP2C19, UGT2B7, UGT2B17 | NOD1 904/4885CXCL8 2525/4885TP53 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.