Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.56 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5465698 | 0.92 | PRMT5 (0.59) | PRMT5TLR8KMT2ATP53HTT | |
| SCHEMBL5453935 | 0.85 | TLR8 (0.66) | PRMT5TLR8HTTCXCR4NOD1 | |
| SCHEMBL5453997 | 0.83 | TLR8 (0.53) | TLR8KMT2ACXCR4GLATDP1 | |
| SCHEMBL5141398 | 0.81 | PRMT5 (0.56) | PRMT5TLR8KMT2ATP53HTT | |
| SCHEMBL5463706 | 0.78 | PRMT5 (0.63) | PRMT5TLR8KMT2ATP53HTT | |
| SCHEMBL5456471 | 0.77 | NOD1 (0.60) | PRMT5KMT2ATP53HTTHPGD | |
| SCHEMBL5456420 | 0.77 | CXCR4 (0.73) | TLR8KMT2ATP53HTTCXCR4 | |
| SCHEMBL5473914 | 0.75 | PRMT5 (0.49) | PRMT5TLR8CXCR4ALDH1A1NOD1 | |
| Hydrochloric Acid SCHEMBL11710372 | 0.75 | PRMT5 (0.49) | PRMT5TLR8KMT2ATP53CXCR4 | |
| SCHEMBL5472851 | 0.74 | PRMT5 (0.48) | PRMT5TLR8KMT2ATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | ABBOTT LABORATORIES | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | CYP2C19, UGT2B7, UGT2B17 | PRMT5 2145/4885TLR8 3837/4885KMT2A 1857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.