Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 1/20 | 0.43 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.43 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357322 | 0.82 | FFAR4 (0.44) | PER2CRY1CRY2RAB9ANPC1 | |
| SCHEMBL23733163 | 0.73 | FFAR4 (0.42) | PER2CRY1CRY2NOTUMTDP1 | |
| SCHEMBL12536870 | 0.73 | DRD2 (0.48) | PER2CRY1CRY2RAB9AMAPT | |
| SCHEMBL23732686 | 0.72 | FFAR4 (0.42) | PER2CRY1CRY2RAB9ANPC1 | |
| SCHEMBL14544862 | 0.72 | PER2 (0.52) | PER2CRY1CRY2RAB9AMAPT | |
| SCHEMBL12601141 | 0.69 | PER2 (0.52) | PER2CRY1CRY2RAB9AMAPT | |
| SCHEMBL1899017 | 0.68 | FFAR4 (0.38) | PER2CRY1CRY2RAB9AMAPT | |
| SCHEMBL2124966 | 0.67 | NOTUM (0.60) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| SCHEMBL23732692 | 0.66 | FFAR4 (0.46) | PER2CRY1CRY2RAB9ANPC1 | |
| SCHEMBL8283892 | 0.66 | PER2 (0.59) | PER2CRY1CRY2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070135413-A1 | TREATMENT OF GLIAL TUMORS WITH GLUTAMATE ANTAGONISTS | NEDERGAARD MAIKEN | 2007-06-14 | — | — | US | disclosed |