Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 9/20 | 0.68 |
| ▸ | NPC1 | O15118 | 6/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.67 |
| ▸ | MIF | P14174 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2634977 | 0.86 | SMN1; SMN2 (0.87) | SMN1; SMN2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL11314623 | 0.86 | NOX1 (0.59) | SMN1; SMN2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL2682040 | 0.84 | RAB9A (0.71) | SMN1; SMN2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL6816405 | 0.84 | SMN1; SMN2 (0.72) | SMN1; SMN2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL8341613 | 0.84 | KMT2A (0.72) | SMN1; SMN2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL11173864 | 0.84 | RAB9A (0.75) | SMN1; SMN2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL5457318 | 0.80 | RAB9A (1.00) | SMN1; SMN2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL6816396 | 0.79 | RAB9A (0.71) | SMN1; SMN2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL5081276 | 0.79 | NOX1 (0.85) | SMN1; SMN2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL8956349 | 0.79 | NOX1 (0.85) | SMN1; SMN2KMT2AMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |