Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 1.00 |
| ▸ | NPC1 | O15118 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 0.77 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | F2 | P00734 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | STAT1 | P42224 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456563 | 0.86 | RAB9A (0.75) | RAB9ANPC1KMT2ANPSR1LMNA | |
| SCHEMBL11173864 | 0.83 | RAB9A (0.75) | RAB9ANPC1KMT2ANPSR1LMNA | |
| SCHEMBL2634977 | 0.82 | SMN1; SMN2 (0.87) | RAB9ANPC1KMT2ANPSR1LMNA | |
| SCHEMBL25404786 | 0.82 | ALOX12 (0.72) | RAB9ANPC1KMT2ANPSR1LMNA | |
| SCHEMBL1259295 | 0.81 | CYP1A2 (1.00) | RAB9ANPC1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL2682040 | 0.80 | RAB9A (0.71) | RAB9ANPC1KMT2ANPSR1LMNA | |
| SCHEMBL8167087 | 0.80 | CYP1A2 (0.85) | RAB9ANPC1KMT2ANPSR1LMNA | |
| SCHEMBL8341613 | 0.80 | KMT2A (0.72) | RAB9ANPC1KMT2ANPSR1LMNA | |
| SCHEMBL6816405 | 0.80 | SMN1; SMN2 (0.72) | RAB9ANPC1KMT2ANPSR1LMNA | |
| SCHEMBL5456937 | 0.80 | SMN1; SMN2 (0.72) | RAB9ANPC1KMT2ANPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |