Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.36 |
| ▸ | CBFB | Q13951 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.32 |
| ▸ | RAF1 | P04049 | 2/20 | 0.32 |
| ▸ | BRAF | P15056 | 2/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 2/20 | 0.31 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.31 |
| ▸ | TTBK2 | Q6IQ55 | 2/20 | 0.31 |
| ▸ | TEK | Q02763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5454087 | 0.92 | RAF1 (0.33) | KDRPDE10ARAF1BRAFCSNK1A1 | |
| SCHEMBL5453176 | 0.90 | RIPK1 (0.38) | KDREGLN1PDE10ARAF1BRAF | |
| SCHEMBL5766491 | 0.88 | KDR (0.36) | KDRPDE10ARAF1BRAFCSNK1A1 | |
| SCHEMBL5449919 | 0.80 | KDR (0.36) | KDRCBFBEGLN1PDE10ARAF1 | |
| SCHEMBL5450812 | 0.75 | RIPK1 (0.36) | KDREGLN1TEK | |
| SCHEMBL4164494 | 0.75 | KDR (0.59) | KDRCBFBPDE10ARAF1BRAF | |
| SCHEMBL5450929 | 0.73 | — | — | |
| SCHEMBL4164886 | 0.72 | KDR (0.41) | KDRCBFBPDE10ARAF1BRAF | |
| SCHEMBL5449925 | 0.72 | KDR (0.49) | KDRCBFBPDE10ARAF1BRAF | |
| SCHEMBL5449786 | 0.72 | CBFB (0.34) | CBFBEGLN1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021456-A1 | Aminobenzimidazole derivatives | MERCK PATENT GMBH (DE) | 2007-01-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021456-A1 | Aminobenzimidazole derivatives | TIE1, KDR, FLT1 | KDR 2/4885CBFB 1061/4885EGLN1 319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.