Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.40 |
| ▸ | CBFB | Q13951 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 5/20 | 0.36 |
| ▸ | RAF1 | P04049 | 3/20 | 0.36 |
| ▸ | PTGES | O14684 | 3/20 | 0.35 |
| ▸ | TEK | Q02763 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.34 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5454095 | 0.91 | PDE10A (0.38) | KDRPDE10ACSNK1A1CSNK1DGSK3B | |
| SCHEMBL5453181 | 0.90 | RIPK1 (0.40) | KDRPDE10ACSNK1A1CSNK1DGSK3B | |
| SCHEMBL5449925 | 0.86 | KDR (0.49) | KDRPDE10ACBFBCSNK1A1CSNK1D | |
| SCHEMBL5450819 | 0.79 | PTGES (0.45) | KDRPDE10ACBFBBRAFRAF1 | |
| SCHEMBL5464243 | 0.79 | PTGES (0.40) | KDRPDE10ACBFBBRAFRAF1 | |
| SCHEMBL4164494 | 0.79 | KDR (0.59) | KDRPDE10ACBFBCSNK1A1CSNK1D | |
| SCHEMBL5444078 | 0.78 | PTGES (0.41) | KDRBRAFRAF1PTGESALOX5 | |
| SCHEMBL5796495 | 0.77 | PTGES (0.41) | KDRBRAFRAF1PTGESALOX5 | |
| SCHEMBL4172506 | 0.77 | KDR (0.48) | KDRPDE10ACBFBCSNK1A1CSNK1D | |
| SCHEMBL14595258 | 0.76 | CBFB (0.39) | KDRCBFBCSNK1A1CSNK1DGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021456-A1 | Aminobenzimidazole derivatives | MERCK PATENT GMBH (DE) | 2007-01-25 | — | — | US | claimed |
| US-20070021456-A1 | Aminobenzimidazole derivatives | MERCK PATENT GMBH (DE) | 2007-01-25 | — | — | US | disclosed |
| US-20070021456-A1 | Aminobenzimidazole derivatives | MERCK PATENT GMBH (DE) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021456-A1 | Aminobenzimidazole derivatives | TIE1, KDR, FLT1 | KDR 2/4885PDE10A 4420/4885CBFB 1061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.