Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.68 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4251085 | 0.89 | MAPT (0.70) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL28435408 | 0.85 | EPHX1 (0.83) | ALDH1A1EPHX1HTTMAPTMEN1 | |
| SCHEMBL8372271 | 0.79 | KMT2A (0.77) | ALDH1A1HTTMAPTMEN1KMT2A | |
| SCHEMBL18459114 | 0.78 | KMT2A (0.59) | ALDH1A1HTTMAPTMEN1KMT2A | |
| SCHEMBL13454726 | 0.77 | ALDH1A1 (0.70) | ALDH1A1HTTMAPTMEN1KMT2A | |
| SCHEMBL6155611 | 0.76 | MAPT (0.63) | ALDH1A1EPHX1MAPTMEN1KMT2A | |
| SCHEMBL4254980 | 0.76 | TP53 (0.75) | ALDH1A1HTTMAPTMEN1KMT2A | |
| SCHEMBL5453730 | 0.76 | MAPT (0.78) | ALDH1A1EPHX1HTTMAPTMEN1 | |
| SCHEMBL5445810 | 0.76 | ALDH1A1 (0.64) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL11163863 | 0.76 | EPHX1 (0.65) | ALDH1A1EPHX1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101129295-B | There is the binary initiator system of good storage stability and especially suitable for acidic system | HERAEUS KULZER GMBH (DE) | 2016-02-10 | — | — | CN | disclosed |
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |