SCHEMBL5457542

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6105801	0.86	ALDH1A1 (0.43)	KMT2AMEN1NPSR1HTTNPC1
	SCHEMBL5459574	0.83	TDP1 (0.42)	MAPK14KMT2AMEN1NPSR1HTT
	SCHEMBL5459581	0.83	TDP1 (0.42)	MAPK14KMT2AMEN1NPSR1HTT
	SCHEMBL6107074	0.82	SMN1; SMN2 (0.38)	KMT2AMEN1HTTNPC1RAB9A
	SCHEMBL5459554	0.76	ALOX5 (0.42)	MAPK14CSNK1DCSNK1ENPC1RAB9A
	SCHEMBL6105119	0.71	ALDH1A1 (0.42)	KMT2AMEN1NPSR1HTTALDH1A1
	SCHEMBL6105126	0.71	ALDH1A1 (0.42)	KMT2AMEN1NPSR1HTTALDH1A1
	SCHEMBL5452130	0.71	AXL (0.38)	MAPK14KMT2AMEN1HTTNPC1
	SCHEMBL5379439	0.71	MAPK14 (0.54)	MAPK14KMT2AMEN1NPSR1HTT
	SCHEMBL5448879	0.70	MAPK14 (0.42)	MAPK14CSNK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.