Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 9/20 | 0.71 |
| ▸ | CFTR | P13569 | 1/20 | 0.66 |
| ▸ | TNF | P01375 | 2/20 | 0.57 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RAB7A | P51149 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5457822 | 0.85 | CFTR (0.59) | FLT3CFTRNPC1RAB9AMEN1 | |
| SCHEMBL5467114 | 0.84 | CFTR (0.64) | FLT3CFTRNPC1RAB9AMEN1 | |
| SCHEMBL5448486 | 0.84 | CXCR2 (0.59) | FLT3CFTRMEN1KMT2AMAPT | |
| SCHEMBL5449075 | 0.80 | CFTR (0.66) | FLT3CFTRRAB9AMEN1KMT2A | |
| SCHEMBL5460025 | 0.80 | CFTR (0.55) | FLT3CFTRNPC1RAB9AMEN1 | |
| SCHEMBL19475104 | 0.79 | CFTR (0.65) | CFTRNPC1RAB9AALDH1A1RAB7A | |
| SCHEMBL5460090 | 0.79 | ALDH1A1 (0.74) | FLT3CFTRNPC1RAB9AMEN1 | |
| SCHEMBL16445278 | 0.79 | CFTR (0.66) | FLT3CFTRNPC1RAB9ACNR2 | |
| SCHEMBL5458336 | 0.78 | CFTR (0.58) | FLT3CFTRNPC1RAB9AMEN1 | |
| SCHEMBL5451275 | 0.78 | CFTR (0.53) | FLT3CFTRNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | claimed |
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | TBCA, PARK7, NFATC1 | FLT3 3509/4885CFTR 2030/4885TNF 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.