Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 12/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 9/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 4/20 | 0.49 |
| ▸ | AKT2 | P31751 | 4/20 | 0.49 |
| ▸ | AKT3 | Q9Y243 | 4/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4717393 | 0.89 | RPS6KA5 (0.60) | RPS6KA5ROCK1RPS6KB1CDK2DYRK1A | |
| SCHEMBL4000617 | 0.83 | RPS6KA5 (0.58) | RPS6KA5TSHRMEN1MAPTKMT2A | |
| SCHEMBL4763075 | 0.83 | DHFR (0.41) | RPS6KA5TSHRMEN1MAPTKMT2A | |
| SCHEMBL4760149 | 0.83 | RPS6KA5 (0.64) | RPS6KA5ROCK1RPS6KB1CDK2DYRK1A | |
| SCHEMBL4000248 | 0.81 | ROCK1 (0.62) | RPS6KA5TSHRMEN1MAPTKMT2A | |
| SCHEMBL4716227 | 0.79 | TSHR (0.55) | RPS6KA5TSHRMEN1MAPTKMT2A | |
| SCHEMBL4762207 | 0.77 | RPS6KA5 (0.60) | RPS6KA5ROCK1RPS6KB1CDK2DYRK1A | |
| SCHEMBL4718346 | 0.77 | RPS6KA5 (0.62) | RPS6KA5ROCK1RPS6KB1CDK2DYRK1A | |
| SCHEMBL4715599 | 0.76 | RPS6KA5 (0.58) | RPS6KA5ROCK1RPS6KB1CDK2DYRK1A | |
| SCHEMBL4716932 | 0.76 | ROCK1 (0.56) | RPS6KA5ROCK1RPS6KB1CDK2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123561-A1 | Preparation of 1,7-disubstituted azabensimidazoles as kinase inhibitors | LEE DENNIS | 2007-05-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123561-A1 | Preparation of 1,7-disubstituted azabensimidazoles as kinase inhibitors | TNK2, CDC42BPB, CDC42BPA | RPS6KA5 117/4885TSHR 3762/4885MEN1 2126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.