Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5462591 | 0.92 | MAPT (0.49) | KMT2ANPC1MEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5455735 | 0.92 | MAPT (0.50) | KMT2ANPC1MEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5465117 | 0.87 | KMT2A (0.61) | KMT2ANPC1MEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5464810 | 0.83 | KMT2A (0.54) | KMT2ANPC1MEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5462055 | 0.82 | NAMPT (0.58) | KMT2ANPC1MEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5460880 | 0.82 | MAPT (0.49) | KMT2ANPC1MEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5460920 | 0.82 | KMT2A (0.56) | KMT2ANPC1MEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5455863 | 0.81 | KMT2A (0.62) | KMT2ANPC1MEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5455945 | 0.81 | MAPT (0.57) | KMT2ANPC1MEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5455975 | 0.81 | MAPT (0.58) | KMT2ANPC1MEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | KMT2A 1350/4885NPC1 1089/4885MEN1 1828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.