Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5465924 | 0.91 | KDM4E (0.46) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5463477 | 0.90 | TRPV1 (0.53) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5462591 | 0.88 | MAPT (0.49) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5459861 | 0.84 | MAPT (0.50) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5451470 | 0.84 | MAPT (0.49) | NPC1MAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL5467111 | 0.83 | MAPT (0.51) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5460431 | 0.83 | MAPT (0.54) | NPC1MAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL5464810 | 0.82 | KMT2A (0.54) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5466986 | 0.81 | P2RY1 (0.51) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5460880 | 0.81 | MAPT (0.49) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | NPC1 1089/4885RAB9A 1528/4885MAPT 758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.