Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.78 |
| ▸ | GAA | P10253 | 3/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9963505 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MAPTGAATDP1TSHR | |
| SCHEMBL1402561 | 0.78 | TSHR (0.69) | ALDH1A1GAATSHRKMT2ASMN1; SMN2 | |
| SCHEMBL11124295 | 0.76 | HTT (0.74) | ALDH1A1MAPTGAATDP1TSHR | |
| SCHEMBL14433881 | 0.74 | KMT2A (0.72) | ALDH1A1MAPTGAATDP1KMT2A | |
| SCHEMBL12336937 | 0.74 | TSHR (0.59) | ALDH1A1MAPTGAATDP1TSHR | |
| SCHEMBL8956279 | 0.74 | KMT2A (0.78) | ALDH1A1MAPTGAAKMT2ASMN1; SMN2 | |
| SCHEMBL28877334 | 0.73 | TSHR (0.62) | ALDH1A1TSHRKMT2ASMN1; SMN2LMNA | |
| SCHEMBL11470310 | 0.73 | KMT2A (0.81) | TSHRKMT2ASMN1; SMN2MEN1NAMPT | |
| SCHEMBL5929386 | 0.73 | MALT1 (0.64) | ALDH1A1MAPTGAATDP1TSHR | |
| SCHEMBL11391291 | 0.73 | HTT (1.00) | ALDH1A1MAPTGAATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |