SCHEMBL28877334

SCHEMBL28877334

O=C(C=Cc1ccccc1)NCCN1CCCC1=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.62
KMT2A Q03164 2/20 0.56
ITGB2 P05107 5/20 0.54
ICAM1 P05362 5/20 0.54
ITGAL P20701 5/20 0.54
DRD2 P14416 3/20 0.53
DRD3 P35462 3/20 0.53
MMP1 P03956 1/20 0.52
POLB P06746 1/20 0.52
MMP2 P08253 1/20 0.52
MMP9 P14780 1/20 0.52
RECQL P46063 1/20 0.52
RAB9A P51151 3/20 0.52
NPC1 O15118 2/20 0.52
HPGD P15428 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
LMNA P02545 1/20 0.52
ALDH1A1 P00352 1/20 0.50
EGFR P00533 1/20 0.49
OPRL1 P41146 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28877333 0.82 POLB (0.46) TSHRKMT2AITGB2ICAM1ITGAL
SCHEMBL19146542 0.81 KMT2A (0.58) TSHRKMT2AITGB2ICAM1ITGAL
SCHEMBL11484182 0.80 KMT2A (0.63) KMT2ADRD2DRD3MMP1POLB
SCHEMBL22562956 0.78 KMT2A (0.55) TSHRKMT2AITGB2ICAM1ITGAL
SCHEMBL1402561 0.78 TSHR (0.69) TSHRKMT2AHPGDSMN1; SMN2LMNA
SCHEMBL19146023 0.78 KMT2A (0.57) TSHRKMT2AITGB2ICAM1ITGAL
SCHEMBL19146563 0.76 KMT2A (0.52) TSHRKMT2AITGB2ICAM1ITGAL
SCHEMBL7480244 0.76 HDAC1 (0.46) TSHRKMT2AITGB2ICAM1ITGAL
SCHEMBL7480234 0.76 HDAC1 (0.46) TSHRKMT2AITGB2ICAM1ITGAL
SCHEMBL11590847 0.76 KMT2A (0.86) KMT2AMMP1POLBMMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115252914-B Network interpenetrating drug controlled release super-smooth coating catheter 山东百多安医疗器械股份有限公司 2022-11-29 CN disclosed
CN-115252914-A Network interpenetrating drug controlled release super-smooth coating catheter 山东百多安医疗器械股份有限公司 2022-11-01 CN disclosed