Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R38 | P59533 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10653459 | 0.92 | TAS2R38 (0.48) | TAS2R38ALDH1A1HTTHSD17B10PTGS2 | |
| Acetic Acid SCHEMBL28266501 | 0.87 | TAS2R38 (0.56) | TAS2R38ALDH1A1HTTHSD17B10PTGS2 | |
| SCHEMBL176566 | 0.86 | — | — | |
| SCHEMBL28033889 | 0.83 | — | — | |
| Ammonia Solution, Strong SCHEMBL27448008 | 0.83 | — | — | |
| Hydrogen Sulfide SCHEMBL18152011 | 0.83 | — | — | |
| SCHEMBL28265811 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL11137208 | 0.83 | — | — | |
| Phosphoric Acid SCHEMBL27574311 | 0.79 | TAS2R38 (0.40) | TAS2R38ALDH1A1HSD17B10PTGS2HPGD | |
| Biguanide SCHEMBL4198353 | 0.74 | ACHE (0.40) | TAS2R38ALDH1A1LDHALDHBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |