Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP10 | P09238 | 1/20 | 0.67 |
| ▸ | MMP13 | P45452 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5458054 | 1.00 | MMP10 (0.67) | MMP10MMP13MAPTGAAPOLB | |
| SCHEMBL5449454 | 0.86 | MAPT (0.48) | MMP10MMP13MAPTGAAPOLB | |
| SCHEMBL20547326 | 0.68 | MAOA (0.58) | MAPTGAAPOLBKMT2AMEN1 | |
| SCHEMBL14027233 | 0.67 | POLB (0.83) | MMP10MMP13MAPTGAAPOLB | |
| SCHEMBL10369738 | 0.64 | MAPK1 (0.67) | MMP10MMP13MAPTGAAPOLB | |
| SCHEMBL512500 | 0.64 | GAA (0.64) | MAPTGAAPOLBKMT2AMEN1 | |
| SCHEMBL30018123 | 0.64 | MAPT (1.00) | MMP10MMP13MAPTGAAPOLB | |
| SCHEMBL29406085 | 0.61 | STAT3 (1.00) | MAPTPOLBKMT2AMEN1KDM4E | |
| SCHEMBL4468905 | 0.60 | POLB (0.53) | MAPTGAAPOLBKMT2AMEN1 | |
| SCHEMBL19820836 | 0.60 | POLB (0.54) | MAPTGAAPOLBKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |