MMP10 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL688140	1.00	11/20
SCHEMBL689439	0.72	10/20
SCHEMBL689440	0.72	10/20
SCHEMBL689478	0.72	10/20
SCHEMBL688587	0.62	10/20
SCHEMBL688588	0.62	10/20
SCHEMBL689357	0.52	10/20
SCHEMBL689221	1.00	9/20
SCHEMBL689726	1.00	9/20
SCHEMBL689610	0.87	9/20
SCHEMBL689658	0.79	9/20
SCHEMBL689411	0.78	9/20
Hydrochloric Acid (SCHEMBL689101)	0.68	9/20
Trifluoroacetic Acid (SCHEMBL688891)	0.68	9/20
SCHEMBL687716	1.00	8/20
SCHEMBL688503	0.80	8/20
SCHEMBL689092	0.80	8/20
SCHEMBL689496	0.78	8/20
SCHEMBL688746	0.75	8/20
SCHEMBL688472	0.67	8/20

Clinical trials — most relevant to MMP10 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Doxycycline In Lymphangioleiomyomatosis (LAM)	PHASE4	COMPLETED
Estimation of MMP-8 Levels in GCF and Serum and Its Correlation With Wound Healing and Clinical Outcomes After Coronally Advanced Flap and Subepithelial Connective Tissue Graft for Root Coverage in Recession Defects: A CLINICO-BIOCHEMICAL STUDY	PHASE4	SUSPENDED
Sputum Matrix Metalloproteinases (MMP) mRNA and Montelukast	PHASE2	COMPLETED
A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer	PHASE1	COMPLETED
The Role of Matrix Metalloproteinases (MMPs) in Orthodontic Tooth Movement	PHASE1	COMPLETED
Re-evaluation of Some Old Rheumatoid Arthritis Therapy: A Randomized Controlled Trial	nan	COMPLETED
Periodontal Health in Post COVID-19 Patients	nan	UNKNOWN
Influence of Statins in Artery Aneurysms	nan	UNKNOWN
The Impact of Pregnancy and Pregnancy-associated Hypertension on Human Uterine Myometrial Artery Reactivity	nan	WITHDRAWN
Evaluation of Dentinal Fluid for the Presence of Matrix Metalloproteinase 9 (MMP-9) in Pulpal Inflammation	nan	COMPLETED
Matrix Metalloproteinases After Surgery and/or Radiofrequency Ablation in Patients With Liver Metastases From Colorectal Cancer	nan	COMPLETED
Detection of Cancer-Specific Active Proteases in Blood Via Fluorescence	nan	WITHDRAWN
Biomarkers for Prognosis of Glioblastoma (GBM)	nan	COMPLETED
Case-control Study on Matrix Metalloproteinase Levels in Tissue in Patients With Keloid Scar	nan	COMPLETED
The Effect of Non-surgical Periodontal Therapy Plus Doxycycline on HbA1c in Patients With Type 2 Diabetes Mellitus	nan	COMPLETED
Apoptotic Changes in Gingiva Caused by Smoking	nan	COMPLETED
Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects	nan	AVAILABLE
Role of A Disintegrin and Metalloproteinase (ADAM) in Epithelial Dysfunction	nan	COMPLETED
Matrix Metalloproteinase (MMP) in Heart Failure	nan	COMPLETED
Characterizing the Inflammation Around Dental Implants: Bacterial Infection, Hypersensitivity or Both?	nan	RECRUITING
The Effect of Exercise Training on lncRNA Expression in Rheumatoid Arthritis	nan	RECRUITING
Characterizing Matrix Metalloproteinase-12 (MMP12) in Sputum	nan	RECRUITING
Role and Expression of MXRA5 in Placental Connective Tissue Remodelling in Preeclampsia	nan	UNKNOWN
Pathology, Venous Disease, and Clinical Correlations	nan	UNKNOWN
Abnormal 3-D MRI Flow Patterns in Adolescents Patients With Bicuspid Aortic Valve	nan	COMPLETED
The Effects of Sodium Fluoride and Chlorhexidine Use on Salivary IL-6 and Matrix Metalloproteinase Levels in Children With Active Caries	nan	RECRUITING
Salivary Markers in Periodontal Disorders	nan	COMPLETED
Matrix Metalloproteinases in Patients With Critical Limb Ischemia Undergoing Surgical Revascularization	nan	COMPLETED
miRNA-452 in Patients With Preeclampsia and Its Correlation With MMP-9	nan	COMPLETED
Plasma and Scarring of Diabetic Ulcers	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a MMP10 binder may also engage these)

Protein	Name	Similarity
O55123	—	1.000	O55123 →
P07152	—	1.000	P07152 →
P03957	—	1.000	P03957 →
Q10835	—	0.999	Q10835 →
Q28397	—	0.998	Q28397 →
MMP1	Interstitial collagenase	0.998	landscape →
P28863	—	0.998	P28863 →
Q6Y4Q5	—	0.998	Q6Y4Q5 →
MMP3	Stromelysin-1	0.998	landscape →
P57748	—	0.998	P57748 →
O18767	—	0.997	O18767 →
O62806	—	0.997	O62806 →
P28862	—	0.997	P28862 →
O88766	—	0.997	O88766 →
MMP20	Matrix metalloproteinase-20	0.997	landscape →
P53690	—	0.996	P53690 →
Q95220	—	0.996	Q95220 →
Q10739	—	0.995	Q10739 →
O70138	—	0.995	O70138 →
Q63341	—	0.995	Q63341 →
P21692	—	0.995	P21692 →
P50757	—	0.995	P50757 →
O77656	—	0.994	O77656 →
P28053	—	0.994	P28053 →
MMP13	Collagenase 3	0.994	landscape →
MMP12	Macrophage metalloelastase	0.994	landscape →
MMP14	Matrix metalloproteinase-14	0.994	landscape →
Q9EPL5	—	0.994	Q9EPL5 →
P23097	—	0.994	P23097 →
Q9GLE5	—	0.994	Q9GLE5 →