SCHEMBL5458653

SCHEMBL5458653

COc1cc2c(cc1OC)OCO2

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.64
HPGD P15428 1/20 0.64
ALDH1A1 P00352 4/20 0.51
MAPT P10636 3/20 0.51
HSP90AA1 P07900 2/20 0.51
MITF O75030 1/20 0.51
MAPK1 P28482 1/20 0.51
HTT P42858 1/20 0.51
POLB P06746 1/20 0.47
CYP3A4 P08684 2/20 0.47
KMT2A Q03164 1/20 0.46
NPC1 O15118 1/20 0.45
TP53 P04637 1/20 0.45
PKM P14618 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
ACHE P22303 1/20 0.45
USP2 O75604 1/20 0.45
HSP90AB1 P08238 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL785194 0.86 LMNA (0.56) LMNAHPGDALDH1A1MAPTHSP90AA1
SCHEMBL5997064 0.84 LMNA (0.55) LMNAHPGDALDH1A1MAPTHSP90AA1
SCHEMBL212999 0.84 LMNA (0.55) LMNAHPGDALDH1A1MAPTHSP90AA1
SCHEMBL4132058 0.84 LMNA (0.55) LMNAHPGDALDH1A1MAPTHSP90AA1
SCHEMBL8111501 0.84 LMNA (0.55) LMNAHPGDALDH1A1MAPTHSP90AA1
SCHEMBL8803195 0.84 LMNA (0.55) LMNAHPGDALDH1A1MAPTHSP90AA1
SCHEMBL30720219 0.84 LMNA (0.55) LMNAHPGDALDH1A1MAPTHSP90AA1
Hydrochloric Acid SCHEMBL2767291 0.83 LMNA (0.53) LMNAHPGDALDH1A1MAPTHSP90AA1
SCHEMBL15145044 0.83 LMNA (0.58) LMNAHPGDALDH1A1MAPTHSP90AA1
SCHEMBL10687082 0.82 NQO1 (0.58) LMNAHPGDALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070110726-A1 Rust disease control by Aphanocladium album and/or Beauveria brongniartii PHYTOMYCO RESEARCH CORPORATION (US) 2007-05-17 US disclosed
US-20070110726-A1 Rust disease control by Aphanocladium album and/or Beauveria brongniartii PHYTOMYCO RESEARCH CORPORATION (US) 2007-05-17 US disclosed
US-20070110726-A1 Rust disease control by Aphanocladium album and/or Beauveria brongniartii PHYTOMYCO RESEARCH CORPORATION (US) 2007-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070110726-A1 Rust disease control by Aphanocladium album and/or Beauveria brongniartii ERG28, HLA-A, GET3 LMNA 3658/4885HPGD 3118/4885ALDH1A1 4121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.